Contrasting Tenaya Therapeutics (NASDAQ:TNYA) & IN8bio (NASDAQ:INAB)

Tenaya Therapeutics (NASDAQ:TNYA) and IN8bio (NASDAQ:INAB) are both small-cap medical companies, but which is the better business? We will compare the two companies based on the strength of their profitability, valuation, dividends, earnings, analyst recommendations, institutional ownership and risk.

Institutional & Insider Ownership

90.5% of Tenaya Therapeutics shares are held by institutional investors. Comparatively, 92.1% of IN8bio shares are held by institutional investors. 32.8% of Tenaya Therapeutics shares are held by company insiders. Comparatively, 15.5% of IN8bio shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Profitability

This table compares Tenaya Therapeutics and IN8bio’s net margins, return on equity and return on assets.

	Net Margins	Return on Equity	Return on Assets
Tenaya Therapeutics	N/A	-80.97%	-67.83%
IN8bio	N/A	-173.12%	-118.40%

Analyst Recommendations

This is a breakdown of current recommendations for Tenaya Therapeutics and IN8bio, as provided by MarketBeat.

	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Tenaya Therapeutics	0	0	6	0	3.00
IN8bio	0	0	2	0	3.00

Tenaya Therapeutics currently has a consensus price target of $15.25, suggesting a potential upside of 761.58%. IN8bio has a consensus price target of $10.00, suggesting a potential upside of 4,342.47%. Given IN8bio’s higher probable upside, analysts clearly believe IN8bio is more favorable than Tenaya Therapeutics.

Valuation and Earnings

This table compares Tenaya Therapeutics and IN8bio”s revenue, earnings per share (EPS) and valuation.

	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Tenaya Therapeutics	N/A	N/A	-$124.08 million	($1.53)	-1.16
IN8bio	N/A	N/A	-$30.01 million	($0.91)	-0.25

Tenaya Therapeutics is trading at a lower price-to-earnings ratio than IN8bio, indicating that it is currently the more affordable of the two stocks.

Volatility & Risk

Tenaya Therapeutics has a beta of 2.35, indicating that its share price is 135% more volatile than the S&P 500. Comparatively, IN8bio has a beta of -0.05, indicating that its share price is 105% less volatile than the S&P 500.

About Tenaya Therapeutics

Tenaya Therapeutics, Inc., a biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States. It develops its products through gene editing, cellular regeneration, and gene addition. The company is developing TN-201, a gene therapy for myosin binding protein C3-associated hypertrophic cardiomyopathy which is in phase 1 clinical trial; TN-301, a small molecule for heart failure with preserved ejection fraction which is in phase 1 clinical trial; and TN-401, a gene therapy for plakophilin 2-associated arrhythmogenic right ventricular cardiomyopathy which is in preclinical stage. It also develops an adeno-associated virus-based gene therapy designed to deliver the dworf gene for patient with dilated cardiomyopathy; and reprogramming program for heart failure due to prior myocardial infarction. Tenaya Therapeutics, Inc. was incorporated in 2016 and is headquartered in South San Francisco, California.

About IN8bio

IN8bio, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of gamma-delta T cell therapies for the treatment of cancers. Its lead product candidates include INB-200, a genetically modified autologous gamma-delta T cell product candidate that is in Phase I clinical trial for the treatment of glioblastoma and solid tumors; INB-100, an allogeneic product candidate, which is in Phase I clinical trial to treat patients with acute leukemia undergoing hematopoietic stem cell transplantation; and INB-400, which is in Phase 2 clinical trial to treat newly diagnosed GBM. It also develops INB-300, INB-410, and INB-500 that are in preclinical Phase for treatment of various solid tumor cancers. The company was formerly known as Incysus Therapeutics, Inc. and changed its name to IN8bio, Inc. in August 2020. IN8bio, Inc. was incorporated in 2016 and is headquartered in New York, New York.